BOP1 Recombinant monoclonal antibody proteintech 82742-3-RR
$449.00
In stock
SKU
82742-3-RR
KIAA0124, block of proliferation 1, 3A4
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse, rat | Immunogen: block of proliferation 1 |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 117 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BOP1 |
| Conjugate: Unconjugated | Gene Symbol: 23246 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_3086524 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse, Rat | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: Block of Proliferation 1(BOP1) protein was first isolated from a mouse, and the truncation protein may led to cell cycle arrest. Bop1 plays a role in processing of the 28S and 5.8S rRNAs (ribosomal RNAs) to regulate ribosome biogenesis. And Bop1 also act as a component of Pes1/Bop1/WDR21 (PeBoW) complex for mature 60S ribosome, and consequently acts during cell division at G1 checkpoints (PMID:18670790; PMID:26940494). What's more, abnormal expression of BOP1 was associated with liver or colorectal cancers (PMID:16804918). The molecular weight of the protein we detected was slightly higher, about 117 kd, which is also seen in the article (PMID: 30100995). |