USP36 Polyclonal antibody proteintech 14783-1-AP
$449.00
In stock
SKU
14783-1-AP
Deubiquitinating enzyme 36, DUB1, EC:2.3.2.-, KIAA1453, Ubiquitin carboxyl-terminal hydrolase 36
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Human And More (1) | Immunogen: CatNo: Ag6411 Product name: Recombinant human USP36 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-285 aa of BC038983 Sequence: MPIVDKLKEALKPGRKDSADDGELGKLLASSAKKVLLQKIEFEPASKSFSYQLEALKSKYVLLNPKTEGASRHKSGDDPPARRQGSEHTYESCGDGVPAPQKVLFPTERLSLRWERVFRVGAGLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSCHQGSFCMLCVMQNHIVQAFANSGNAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQKACLNGCAKCVLPHPPSQGFGHLFYMVAAEHSYGNSQPGTFLPRLPLGRRGRICLWVLKLLEPK Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, CoIP, ELISA | Observed Molecular Weight: 1123 aa, 123 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC038983 |
| Conjugate: Unconjugated | Gene Symbol: USP36 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 57602 |
| Application: Western Blot (WB) | RRID: AB_2213357 |
| Dilution: WB : 1:500-1:1000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: USP36(Ubiquitin carboxyl-terminal hydrolase 36) is also named as KIAA1453, FLJ12851, DUB1 and belongs to the peptidase C19 family. It regulates the transcription and processing of rRNA by deubiquitylating various proteins involved in these processes, and the aberrant nucleolar structure in its absence is secondary to deficient ribosome biogenesis. USP36 plays a crucial role in regulating the structure and function of nucleoli.(PMID:19208757). The ubiquitin-specific protease that is required in germline, epithelial, and intestinal stem cells(PMID:19039105). It has 2 isoforms produced by alternative splicing. |
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