MAP2K3 Recombinant monoclonal antibody proteintech 80137-1-RR
$449.00
In stock
SKU
80137-1-RR
MEK3, 3O10, Dual specificity mitogen-activated protein kinase kinase 3, EC:2.7.12.2, MAP kinase kinase 3
| Host / Isotype: Rabbit / IgG | Class: Recombinant |
| Reactivity: human, mouse, rat, zebrafish | Immunogen: Peptide Predict reactive species |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 347 aa, 39 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC032478 |
| Conjugate: Unconjugated | Gene Symbol: MAP2K3 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 5606 |
| Application: Western Blot (WB) | RRID: AB_2918868 |
| Dilution: WB : 1:2000-1:10000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat, Zebrafish | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: MAP2K3, also named MKK3, is a member of?dual specificity kinase group and serves as a specific activator of p38 MAPK with MKK6. MKK3 can be phosphorylated by cytokines and environmental stress at sites Ser189 and Thr193 by MKKK proteins (MEKK 1-4). MKK3 plays a key role in cell differentiation, motility, division and death. It has been reported that MKK3 targeting may represent an effective and potentially safe therapeutic strategy to selectively kill cancer cells in colorectal cancer patients. (PMID:?31695024, 30770795, 26805700, 8622669) |
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