HARS Recombinant monoclonal antibody proteintech 83497-1-RR

$449.00
In stock
SKU
83497-1-RR

 

240495C1, EC:6.1.1.21, HARS1, HisRS, Histidine--tRNA ligase, cytoplasmic

Host / Isotype: Rabbit / IgG Class: Recombinant
Reactivity: human Immunogen: CatNo: Ag9333 Product name: Recombinant human HARS protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-282 aa of BC011807 Sequence: MAERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKGTRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQGGELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQ Predict reactive species
 Applications: WB, IHC, IF/ICC, FC (Intra), ELISA Observed Molecular Weight: 509 aa, 57 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC011807
Conjugate: Unconjugated Gene Symbol: HARS
Tested Applications: Positive WB detected in Gene ID (NCBI): 3035
Application: Western Blot (WB) RRID: AB_3671124
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: HARS is a cytoplasmic enzyme that belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. HARS is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis.

 

 

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