BCL6 Recombinant monoclonal antibody proteintech 81754-1-RR
$449.00
In stock
SKU
81754-1-RR
BCL-6, 3K6, B cell CLL/lymphoma 6, B cell lymphoma 6 protein, B-cell lymphoma 5 protein
| Host / Isotype: Rabbit / IgG | Class: Antibody |
| Reactivity: human, mouse | Immunogen: B-cell CLL/lymphoma 6 |
| Applications: WB, IHC, FC (Intra), IP, ELISA, ChIP-qPCR | Observed Molecular Weight: 79-95 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BCL6 |
| Conjugate: Unconjugated | Gene Symbol: 604 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_2935576 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Liquid |
| Tested Reactivity: Human, Mouse | Form: Protein A purification |
| Host / Isotype: Recombinant | Background Information: BCL6, a zinc finger transcription factor, contains an N-terminal BTB/POZ domain and C-terminal zinc finger DNA-binding motifs and represses transcription of a wide range of target proteins and microRNAs. BCL6 protein has been reported as a master regulator of B lymphocyte development and growth, and altered BCL6 protein expression was implicated in pathogenesis of diverse human hematologic malignancies, especially in the diffuse large B cell lymphoma (DLBCL). BCL6 is required for the development of T follicular helper T cells (TFH), a helper T cell subset required for the formation of mature and productive GCs. BCL6 has also been shown to play important regulatory roles in macrophages. |
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