IFI16 Monoclonal antibody proteintech 67790-1-Ig

$449.00
In stock
SKU
67790-1-Ig

 

Ifi 16, IFI16, IFNGIP1, PYHIN2

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: Human And More (1) Immunogen: CatNo: Ag30314 Product name: Recombinant human IFI16 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 580-729 aa of BC017059 Sequence: VCRNGFLEVYPFTLVADVNADRNMEIPKGLIRSASVTPKINQLCSQTKGSFVNGVFEVHKKNVRGEFTYYEIQDNTGKMEVVVHGRLTTINCEEGDKLKLTCFELAPKSGNTGELRSVIHSHIKVIKTRKNKKDILNPDSSMETSPDFFF Predict reactive species
 Applications: WB, IHC, IF/ICC, ELISA Observed Molecular Weight: 729 aa, 82 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC017059
Conjugate: Unconjugated Gene Symbol: IFI16
Tested Applications: Positive WB detected in Gene ID (NCBI): 3428
Application: Western Blot (WB) RRID: AB_2918554
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: IFI16 is a member of a family of interferon-inducible nuclear proteins involved in transcriptional regulation functions as a transcriptional repressor. IFI16 may be involved in TP53-mediated transcriptional activation by enhancing TP53 sequence-specific DNA binding and modulating TP53 phosphorylation status. It has been reported that IFI16 participates in the regulation of autophagy, TP53-mediated cell death and innate immune response. IFI16 has different isoforms and 67790-1-Ig antibody detects proteins around 85-95 kDa in SDS-PAGE similar to papers. (PMID:?9718316, 14990579, 11146555, 22046441)

 

 

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