GDF10 Monoclonal antibody proteintech 66371-1-Ig
$449.00
In stock
SKU
66371-1-Ig
| Host / Isotype: Mouse / IgG2a | Class: Monoclonal |
| Reactivity: human, pig, rat | Immunogen: CatNo: Ag4906 Product name: Recombinant human GDF10 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-288 aa of BC028237 Sequence: MALAPPPRGLWQAKDISPIVKAARRDGELLLSAQLDSEERDPGVPRPSPYAPYILVYANDLAISEPNSVAVTLQRYDPFPAGDPEPRAAPNNSADPRVRRAAQATGPLQDNELPGLDERPPRAHAQHFHKHQLWPSPFRALKPRPGRKDRRKKGQEVFMAASQVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVDTCACR Predict reactive species |
| Applications: WB, ELISA | Observed Molecular Weight: 53 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC028237 |
| Conjugate: Unconjugated | Gene Symbol: GDF10 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 2662 |
| Application: Western Blot (WB) | RRID: AB_2881750 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: human, pig, rat | Form: Liquid |
| Host / Isotype: Mouse / IgG2a | Background Information: Growth differentiation factor-10 (GDF10), also known as BMP3b, is a member of the transforming growth factor-b (TGF-b) superfamily. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. GDF10 plays a role in head formation and may have multiple roles in skeletal morphogenesis. Additionally, GDF10 may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer. |
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