CD31 Polyclonal antibody proteintech 28083-1-AP
$449.00
In stock
SKU
28083-1-AP
Pecam, PECAM 1, Pecam1, PECAM-1
| Host / Isotype: Rabbit / IgG | Class: Polyclonal |
| Reactivity: Mouse And More (1) | Immunogen: CatNo: Ag27828 Product name: Recombinant mouse Pecam1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 51-276 aa of NM_001032378 Sequence: MISTTSKSRSQHRVLFYKDDAMVYNVTSREHTESYVIPQARVFHSGKYKCTVMLNNKEKTTIEYEVKVHGVSKPKVTLDKKEVTEGGVVTVNCSLQEEKPPIFFKIEKLEVGTKFVKRRIDKTSNENFVLMEFPIEAQDHVLVFRCQAGILSGFKLQESEPIRSEYVTVQESFSTPKFEIKPPGMIIEGDQLHIRCIVQVTHLVQEFTEIIIQKDKAIVATSKQSSE Predict reactive species |
| Applications: WB, IHC, IF-P, IF-Fro, ELISA | Observed Molecular Weight: 81 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_001032378 |
| Conjugate: Unconjugated | Gene Symbol: CD31 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 18613 |
| Application: Western Blot (WB) | RRID: AB_2881055 |
| Dilution: WB : 1:1000-1:8000 | Conjugate: Unconjugated |
| Tested Reactivity: Mouse | Form: Liquid |
| Host / Isotype: Rabbit / IgG | Background Information: Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489). |
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