CD27 Monoclonal antibody proteintech 66308-1-Ig
$449.00
In stock
SKU
66308-1-Ig
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human, pig | Immunogen: CatNo: Ag24537 Product name: Recombinant human CD27 protein Source: e coli.-derived, PET30a Tag: 6*His Domain: 1-260 aa of BC012160 Sequence: MARPHPWWLCVLGTLVGLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCNSGLLVRNCTITANAECACRNGWQCRDKECTECDPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTLADFRQLPARTLSTHWPPQRSLCSSDFIRILVIFSGMFLVFTLAGALFLHQRRKYRSNKGESPVEPAEPCRYSCPREEEGSTIPIQEDYRKPEPACSP Predict reactive species |
| Applications: WB, IHC, IF-P, FC, ELISA | Observed Molecular Weight: 29 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC012160 |
| Conjugate: Unconjugated | Gene Symbol: CD27 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 939 |
| Application: Western Blot (WB) | RRID: ENSG00000139193 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: AB_2881690 |
| Tested Reactivity: Human, Pig | Form: Unconjugated |
| Host / Isotype: Mouse / IgG1 | Background Information: CD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells, and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity (PMID: 11062504). It is a receptor for CD70 (CD27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways, as well as the JNK pathway (PMID: 19426224). CD27 may also play a role in apoptosis through association with SIVA1. |
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