CA3 Monoclonal antibody proteintech 66608-1-Ig
$449.00
In stock
SKU
66608-1-Ig
| Host / Isotype: Mouse / IgG2b | Class: Monoclonal |
| Reactivity: human, mouse, rat, pig, rabbit | Immunogen: CatNo: Ag7513 Product name: Recombinant human CA3 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-260 aa of BC004897 Sequence: MAKEWGYASHNGPDHWHELFPNAKGENQSPIELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNRVVRASFK Predict reactive species |
| Applications: WB, IHC, IF-P, ELISA | Observed Molecular Weight: 29 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC004897 |
| Conjugate: Unconjugated | Gene Symbol: CA3 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 761 |
| Application: Western Blot (WB) | RRID: AB_2881968 |
| Dilution: WB : 1:20000-1:100000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat, Pig, Rabbit | Form: Liquid |
| Host / Isotype: Mouse / IgG2b | Background Information: Carbonic anhydrase III (CA3), which belongs to the alpha-carbonic anhydrase family, is a cytoplasmic enzyme that exhibits a relatively low carbon dioxide hydratase activity. It is expressed at a very high level in skeletal muscle, where physical exercise has been shown to increase free radical production. In addition to its carbon dioxide hydratase activity, CA3 has been demonstrated to have a carboxyl esterase activity and phosphatase activity, which suggests that it is a tyrosine phosphatase (PMID: 10064618). CA3 was found to be localized in Type-I muscle fibers and could be used as a marker for abnormal Type-I muscle fibers in several neuromuscular diseases (PMID: 6221502). |
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