B7?H4 Monoclonal antibody proteintech 66817-1-Ig
$449.00
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66817-1-Ig
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human, mouse, rat | Immunogen: CatNo: Ag27751 Product name: Recombinant human VTCN1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-187 aa of BC065717 Sequence: MFRGRTAVFADQVIVGNASLRLKNVQLTDAGTYKCYIITSKGKGNANLEYKTGAFSMPEVNVDYNASSETLRCEAPRWFPQPTVVWASQVDQGANFSEVSNTSFELNSENVTMKVVSVLYNVTINNTYSCMIENDIAKATGDIKVTESEIKRRSHLQLLNSKASLCVSSFFAISWALLPLSPYLMLK Predict reactive species |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 282 aa, 31 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC065717 |
| Conjugate: Unconjugated | Gene Symbol: B7-H4 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 79679 |
| Application: Western Blot (WB) | RRID: AB_2882160 |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: B7?H4 also named VTCN1, B7X, or B7S1 is a 282 amino acid protein, which contains 2 immunoglobulin-like domains and belongs to the immunoglobulin superfamily. B7?H4 negatively regulates T-cell mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. B7?H4 is a single-pass type I membrane protein, which is over-expressed in breast, ovarian, endometrial, renal cell and non-small-cell lung cancers. The predicted molecular weight of B7?H4 is 31 kDa. The glycosylated B7?H4 is 50 to 80 kDa, and the non-glycosylated form is 28 kDa. |
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