ARHGDIB Monoclonal antibody proteintech 66054-1-Ig

$449.00
In stock
SKU
66054-1-Ig

 

Host / Isotype: Mouse / IgG2b Class: Monoclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag9091 Product name: Recombinant human ARHGDIB protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-201 aa of BC009200 Sequence: MTEKAPEPHVEEDDDDELDSKLNYKPPPQKSLKELQEMDKDDESLIKYKKTLLGDGPVVTDPKAPNVVVTRLTLVCESAPGPITMDLTGDLEALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKATFMVGSYGPRPEEYEFLTPVEEAPKGMLARGTYHNKSFFTDDDKQDHLSWEWNLSIKKEWTE Predict reactive species
 Applications: WB, IHC, IF-P, ELISA Observed Molecular Weight: 201 aa, 23 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC009200
Conjugate: Unconjugated Gene Symbol: ARHGDIB
Tested Applications: Positive WB detected in Gene ID (NCBI): 397
Application: Western Blot (WB) RRID: AB_11045657
Dilution: WB : 1:10000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Mouse / IgG2b Background Information: ARHGDIB, also known as RhoGDI2, is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. It is mainly in hematopoietic, endothelial, and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types, such as bladder, lung and lymphoma, but is upregulated in prostate and gastric cancer.

 

 

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