CoraLite? Plus 488 Anti-Mouse TCR Beta (H57-597) proteintech CL488-65106
$137.00
In stock
SKU
CL488-65106
| Host / Isotype: Armenian Hamster / IgG | Class: Antibody |
| Reactivity: mouse | Immunogen: T-cell receptor beta chain |
| Applications: IF/ICC, FC | Observed Molecular Weight: 21577 |
| Formulation: PBS, Azide, BSA | GenBank Accession Number: CoraLite? Plus 488 Fluorescent Dye |
| Conjugate: CoraLite? Plus 488 | Gene Symbol: 493 nm / 522 nm |
| Tested Applications: Positive IF/ICC detected in | Gene ID (NCBI): Liquid |
| Application: Immunofluorescence (IF)/ICC | RRID: Affinity purification |
| Dilution: IF/ICC : 1:150-1:600 | Conjugate: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. |
| Tested Reactivity: Mouse | Form: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
| Host / Isotype: Monoclonal | Background Information: T-cell receptor (TCR) consists of heterodimeric glycoproteins (TCR alpha/beta or gamma/delta) that demonstrate homology with immunoglobulins (PMID: 2144901). TCR beta is a member of the immunoglobulin superfamily and is expressed on alpha/beta TCR-bearing T cells and thymocytes. The TCR heterodimers are noncovalently associated with CD3. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta (PMID: 1826255). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657). |
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