Anti-Mouse CD45R (B220) (RA3-6B2) proteintech 65139-1-Ig
$50.00
In stock
SKU
65139-1-Ig
| Host / Isotype: Rat / IgG2a, kappa | Class: Monoclonal |
| Reactivity: mouse | Immunogen: Abelson murine leukemia virus-induced pre-B tumor cells Predict reactive species |
| Applications: IHC, IF/ICC, FC | Observed Molecular Weight: BC028512 |
| Formulation: PBS, Azide | GenBank Accession Number: 19264 |
| Conjugate: Unconjugated | Gene Symbol: AB_2918426 |
| Tested Applications: Positive IHC detected in | Gene ID (NCBI): Unconjugated |
| Application: Immunohistochemistry (IHC) | RRID: Liquid |
| Dilution: IHC : 1:1000-1:4000 | Conjugate: Affinity purification |
| Tested Reactivity: Mouse | Form: P06800 |
| Host / Isotype: Rat / IgG2a, kappa | Background Information: CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45R (B220) is an isoform of CD45, expressed on murine B-lineage cells (except for plasma cells) and on a small sub-population of T cells (PMID: 6975314; 15712182). It is commonly used as a pan B-cell marker in mice. CD45R is also expressed on activated T cells and NK cell subsets (PMID: 7514808; 17923504). The RA3-6B2 clone reacts with human and mouse CD45R. |
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