Anti-Mouse CD45.2 (104) proteintech 65072-1-Ig
$67.00
In stock
SKU
65072-1-Ig
| Host / Isotype: Mouse / IgG2a, kappa | Class: Antibody |
| Reactivity: mouse | Immunogen: protein tyrosine phosphatase, receptor type, C |
| Applications: FC | Observed Molecular Weight: CD45 |
| Formulation: PBS, Azide | GenBank Accession Number: AB_2918378 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Liquid |
| Application: Flow Cytometry (FC) | RRID: Affinity purification |
| Dilution: FC : 0.5 ug per 10^6 cells in 100 μl suspension | Conjugate: P06800 |
| Tested Reactivity: Mouse | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Monoclonal | Background Information: CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). Allelic variants of mouse CD45, CD45.1 (Ly5.1) and CD45.2 (Ly5.1), have been established as a marker system to track haematopoietic cells following congenic mouse bone marrow transplants (PMID: 28615666). CD45.2 is the common form and is expressed by most of the established strains, while CD45.1 is found in only a few like the SJL mouse strain (PMID: 3489673). |
Reviews
Write Your Own Review