Anti-Mouse CD44 (IM7) proteintech 65117-1-Ig
$82.00
In stock
SKU
65117-1-Ig
| Host / Isotype: Rat / IgG2b, kappa | Class: Antibody |
| Reactivity: Human, Mouse | Immunogen: CD44 antigen |
| Applications: IHC, IF/ICC, FC | Observed Molecular Weight: Cd44 |
| Formulation: PBS, Azide | GenBank Accession Number: AB_2918413 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive IF/ICC detected in | Gene ID (NCBI): Liquid |
| Application: Immunofluorescence (IF)/ICC | RRID: Protein A purification |
| Dilution: IF/ICC : 1:50-1:400 | Conjugate: P15379 |
| Tested Reactivity: Human, Mouse | Form: PBS with 0.09% sodium azide, pH 7.3. |
| Host / Isotype: Monoclonal | Background Information: CD44 is a type I transmembrane glycoprotein expressed on embryonic stem cells and in various levels on other cell types including connective tissues and bone marrow. CD44 expression is also upregulated in subpopulations of cancer cells and is recognized as a molecular marker for cancer stem cells (PMID: 29747682). It is a cell-surface receptor that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands (PMID: 10694938). Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. |