Anti-Human CD107b / LAMP2 (H4B4) proteintech 65053-1-Ig
$68.00
In stock
SKU
65053-1-Ig
| Host / Isotype: Mouse / IgG1, kappa | Class: Monoclonal |
| Reactivity: human | Immunogen: Human adherent peripheral blood cells Predict reactive species |
| Applications: IF/ICC, FC (Intra) | Observed Molecular Weight: 45 kDa |
| Formulation: PBS, Azide | GenBank Accession Number: LAMP2 |
| Conjugate: Unconjugated | Gene Symbol: 3920 |
| Tested Applications: Positive IF/ICC detected in | Gene ID (NCBI): ENSG00000005893 |
| Application: Immunofluorescence (IF)/ICC | RRID: AB_2881469 |
| Dilution: IF/ICC : 1:400-1:1600 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG1, kappa | Background Information: LAMP2 (CD107b) is a Lysosomal membrane glycoprotein. LAMP2 is extensively glycosylated with asparagine-linked oligosaccharides which protect it from intracellular proteolysis (PMID: 10521503). Although LAMP-2 is localized primarily in the endosome-lysosomal membrane of cells, it is also found on the plasma membrane under certain circumstances, e.g., after platelet activation, during granulocytic differentiation and activation, and in some tumor cells (PMID: 12221139). LAMP is involved in lysosomal stability and autophagy (PMID: 12221139). This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may play a role in tumor cell metastasis (PMID 9426697). |
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