SERPINB9 Monoclonal antibody proteintech 67950-1-Ig

$449.00
In stock
SKU
67950-1-Ig

 

CAP 3, CAP3, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI 9, PI9, Serpin B9, SERPINB9

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: Human, Mouse, Rat And More (2) Immunogen: CatNo: Ag6719 Product name: Recombinant human SERPINB9 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-376 aa of BC002538 Sequence: METLSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP Predict reactive species
 Applications: WB, IHC, IF/ICC, ELISA Observed Molecular Weight: 42 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC002538
Conjugate: Unconjugated Gene Symbol: SERPINB9
Tested Applications: Positive WB detected in Gene ID (NCBI): 5272
Application: Western Blot (WB) RRID: AB_2918702
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: SERPINB9, also named as PI-9, belongs to the serpin family. SERPINB9 is an intracellular inhibitor of granzyme B (grB) that protects cytotoxic lymphocytes from grB-mediated death. It has a nucleo-cytoplasmic distribution and is produced in CD8+ T cells and natural killer cells (PMID: 28024184). Also, SERPINB9 is expressed by vascular SMCs and endothelial cells to avoid GZB-induced apoptosis (PMID: 28743062). The molecular weight of SERPINB9 is 42 kDa.

 

 

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