Pseudouridine Monoclonal antibody proteintech 68578-1-Ig
$449.00
In stock
SKU
68578-1-Ig
Ψ, 5-ribosyluracil
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: Chemical Compound And More (1) | Immunogen: PTG Predict reactive species |
| Applications: Dot Blot, ELISA | |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: AB_3085278 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Positive ELISA detected in | Gene ID (NCBI): Liquid |
| Application: Enzyme-linked Immunosorbent Assay (ELISA) | RRID: Protein G purification |
| Dilution: ELISA : 1:2000-1:20000 | Conjugate: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| Tested Reactivity: Chemical Compound | Form: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA. |
| Host / Isotype: Mouse / IgG1 | Background Information: Pseudouridine is an isomer of the nucleoside uridine in which the uracil is attached via a carbon-carbon instead of a nitrogen-carbon glycosidic bond. Pseudouridine is the most abundant RNA modification in cellular RNA (PMID: 29104216). After transcription and following synthesis, RNA can be modified with over 100 chemically distinct modifications. These can potentially regulate RNA expression post-transcriptionally, in addition to the four standard nucleotides and play a variety of roles in the cell including translation, localization and stabilization of RNA. Pseudouridine in rRNA and tRNA has been shown to fine-tune and stabilize the regional structure and help maintain their functions in mRNA decoding, ribosome assembly, processing and translation (PMID: 10902565, PMID: 23391857, PMID: 28045575). Pseudouridine in snRNA has been shown to enhance spliceosomal RNA-pre-mRNA interaction to facilitate splicing regulation (PMID 27268497). Protocol for Dot Blot: https://www.ptglab.com/protocol/68578-1-IgDotBlot.pdf |
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