Prealbumin/transthyretin Monoclonal antibody proteintech 66108-1-Ig
$449.00
In stock
SKU
66108-1-Ig
Prealbumin, transthyretin, TTR, 1H8C4, ATTR
| Host / Isotype: Mouse / IgG2a | Class: Monoclonal |
| Reactivity: human, mouse | Immunogen: CatNo: Ag19232 Product name: Recombinant human TTR protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-147 aa of BC020791 Sequence: MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE Predict reactive species |
| Applications: WB, IHC, FC (Intra), ELISA | Observed Molecular Weight: 147 aa, 16 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC020791 |
| Conjugate: Unconjugated | Gene Symbol: TTR |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 7276 |
| Application: Western Blot (WB) | RRID: AB_2881507 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Mouse / IgG2a | Background Information: Transthyretin (TTR) is a plasma transport protein for thyroxine and retinol, through the association with retinol-binding protein. It is a homotetrameric protein synthesized mainly in liver, choroid plexus, retinal pigment epithelium, and pancreas.Within the CNS, TTR is the only known protein synthesized solely by the choroid plexus. Mutant and wildtype TTR give rise to various forms of amyloid deposition (amyloidosis). Defects in TTR are the cause of amyloidosis transthyretin-related (AMYL-TTR),hyperthyroxinemia dystransthyretinemic euthyroidal (HTDE) and carpal tunnel syndrome type 1 (CTS1). In addition, positive immunostaining for TTR has been reported as a sensitive diagnostic marker of choroid plexus tumors. TTR can be expressed as monomer (14-16 kDa), dimmer (28-33 kDa), or tetramer around 55-60 kDa. (PMID: 22103483) |
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