NeutraKine? PDGF-BB Mouse McAb proteintech 69020-1-Ig
$339.00
In stock
SKU
69020-1-Ig
PDGFB, PDGFbb, 4G11C7, Becaplermin, PDGF 2
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human | Immunogen: Recombinant Protein Predict reactive species |
| Applications: Neutralization, ELISA, Cell treatment | Observed Molecular Weight: PDGFB |
| Formulation: Sterile PBS | GenBank Accession Number: AB_2918840 |
| Conjugate: Unconjugated | Gene Symbol: Unconjugated |
| Tested Applications: Neutralization | Gene ID (NCBI): Lyophilized Powder |
| RRID: Protein G purification | |
| Conjugate: P01127 | |
| Tested Reactivity: Human | Form: Sterile PBS, pH 7.4. |
| Host / Isotype: Mouse / IgG1 | Background Information: Platelet-derived growth factor (PDGF) belongs to the family of growth factors consisting of four secreted extracellular ligands including PDGF-A, -B, -C and -D. These isoforms, PDGF-AA, PDGF-AB, PDGF-BB, PDGF-CC and PDGF-DD, act via two receptor tyrosine kinases, PDGF receptors alpha and beta. PDGF isoforms stimulate growth, survival and motility of mesenchymal cells and certain other cell type. They have important functions during embryonal development and in the control of tissue homeostasis in the adult. PDGF-BB is one of the most recently studied isoforms and it plays an important role in skeletal development. PDGF-BB stimulates cell-mediated collagen gel contraction. PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors. This antibody can be used to neutralize the bioactivity of PDGF-BB. |
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