MLPH Monoclonal antibody proteintech 66092-1-Ig
$449.00
In stock
SKU
66092-1-Ig
Exophilin 3, Exophilin-3, Melanophilin, SLAC2 A, SLAC2A
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: Human, Pig And More (1) | Immunogen: CatNo: Ag19286 Product name: Recombinant human MLPH protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 8-236 aa of BC001653 Sequence: SKLTDEEAQHVLEVVQRDFDLRRKEEERLEALKGKIKKESSKRELLSDTAHLNETHCARCLQPYQLLVNSKRQCLECGLFTCKSCGRVHPEEQGWICDPCHLARVVKIGSLEWYYEHVKARFKRFGSAKVIRSLHGRLQGGAGPELISEERSGDSDQTDEDGEPGSEAQAQAQPFGSKKKRLLSVHDFDFEGDSDDSTQPQGHSLHLSSVPEARDSPQSLTDESCSEKA Predict reactive species |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 66 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC001653 |
| Conjugate: Unconjugated | Gene Symbol: MLPH |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 79083 |
| Application: Western Blot (WB) | RRID: AB_11232039 |
| Dilution: WB : 1:1000-1:6000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Pig | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: Melanophilin (MLPH) is a member of the exophilin subfamily of Rab effector proteins. MLPH is a modular protein, forming a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. It regulates retention of melanosomes at the peripheral actin cytoskeleton of melanocytes, a process essential for normal mammalian pigmentation. Defects in MLPH are a cause of Griscelli syndrome type 3 (GS3), which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. |
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