MALT1 Monoclonal antibody proteintech 66225-1-Ig
$449.00
In stock
SKU
66225-1-Ig
4D3F6, EC:3.4.22.-, MALT 1, MALT lymphoma-associated translocation, MLT
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: Human And More (1) | Immunogen: CatNo: Ag20632 Product name: Recombinant human MALT1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 126-450 aa of BC030143 Sequence: GIKITVNPESKAVLAGQFVKLCCRATGHPFVQYQWFKMNKEIPNGNTSELIFNAVHVKDAGFYVCRVNNNFTFEFSQWSQLDVCDIPESFQRSVDGVSESKLQICVEPTSQKLMPGSTLVLQCVAVGSPIPHYQWFKNELPLTHETKKLYMVPYVDLEHQGTYWCHVYNDRDSQDSKKVEIIIDELNNLGHPDNKEQTTDQPLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLTEYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSENCLCVQNILKLMQEKETGLNVFLL Predict reactive species |
| Applications: WB, IHC, IF/ICC, FC (Intra), CoIP, ELISA | Observed Molecular Weight: 824 aa, 92 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC030143 |
| Conjugate: Unconjugated | Gene Symbol: MALT1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 10892 |
| Application: Western Blot (WB) | RRID: AB_2881616 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: Mucosa-associated lymphoid tissue lymphoma translocation protein 1 belongs to caspase-like protein superfamily.MALT1 plays a potential role in the regulation of apoptosis and induces NFKB activation and required for the normal development of B cells and for the activation of the IKK complex.It acts as a caspase and mediates additional functions related to T cell activation, cleaving both the ubiquitin editing enzyme,TNFAIP3,and the C terminus of BCL10 .It has two isoforms.Researches showed that inhibition of MALT1 blocks A20 and BCL10 cleavage, reduces NFKB activity, and decreases the expression of NFKB targets BCLXL. |
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