UCH-L1/PGP9.5 Polyclonal antibody proteintech 14730-1-AP

$449.00
In stock
SKU
14730-1-AP

 

PGP9.5, UCHL1, UCHL1/PGP9.5, EC:3.4.19.12, Neuron cytoplasmic protein 9.5

Host / Isotype: Rabbit / IgG Class: Polyclonal
Reactivity: Human, Mouse, Rat And More (4) Immunogen: CatNo: Ag6490 Product name: Recombinant human UCHL1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-223 aa of BC000332 Sequence: MQLKPMEINPEMLNKVLSRLGVAGQWRFVDVLGLEEESLGSVPAPACALLLLFPLTAQHENFRKKQIEELKGQEVSPKVYFMKQTIGNSCGTIGLIHAVANNQDKLGFEDGSVLKQFLSETEKMSPEDRAKCFEKNEAIQAAHDAVAQEGQCRVDDKVNFHFILFNNVDGHLYELDGRMPFPVNHGASSEDTLLKDAAKVCREFTEREQGEVRFSAVALCKAA Predict reactive species
 Applications: WB, IHC, IF/ICC, IF-P, IF-Fro, FC (Intra), IP, CoIP, ELISA Observed Molecular Weight: 25 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC000332
Conjugate: Unconjugated Gene Symbol: UCHL1
Tested Applications: Positive WB detected in Gene ID (NCBI): 7345
Application: Western Blot (WB) RRID: AB_2210497
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat Form: Liquid
Host / Isotype: Rabbit / IgG Background Information: UCHL1(Ubiquitin carboxyl-terminal hydrolase isozyme L1) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. It is present in all neurons(PMID: 6343558). This protein is present in brain at concentrations at least 50 times greater than in other organs and is a major protein component of neuronal cytoplasm (PMID:7217993). And UCHL1 is a Parkinson's disease susceptibility gene (PMID:15048890).

 

 

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