CDC37 Monoclonal antibody proteintech 66420-1-Ig
$449.00
In stock
SKU
66420-1-Ig
CDC37, CDC37A, Hsp90 co chaperone Cdc37, P50CDC37
| Host / Isotype: Mouse / IgG2a | Class: Monoclonal |
| Reactivity: human, mouse, rat | Immunogen: CatNo: Ag0267 Product name: Recombinant human CDC37 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-209 aa of BC000083 Sequence: MVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELDRGCRECKRKVAECQRKLKELEVAEGGKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEKTEEDSEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQV Predict reactive species |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 44 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC000083 |
| Conjugate: Unconjugated | Gene Symbol: CDC37 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 11140 |
| Application: Western Blot (WB) | RRID: AB_2881792 |
| Dilution: WB : 1:2000-1:5000 | Conjugate: Unconjugated |
| Tested Reactivity: human, mouse, rat | Form: Liquid |
| Host / Isotype: Mouse / IgG2a | Background Information: CDC(cell division control) family of proteins are regulatory proteins involved in the processes of cell cycle and proliferation. CDC37, migrated as a protein of 50 kDa in SDS PAGE, is a co-chaperone protein that recruits several immature client kinases to Hsp90 for proper folding. It functions in association with Hsp90, although little is known of its mechanism of action or where it fits into a folding pathway involving other Hsp90 cochaperones. CDC37 up-regulation is a common early event in some localized human cancers. But, the effect of CDC37 dysregulation in human cells is unclear. |
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