CD86 Monoclonal antibody proteintech 68674-2-Ig
$449.00
In stock
SKU
68674-2-Ig
Activation B7 2 antigen, B7 2, B70, BU63, CD28LG2, CD86, CD86 molecule, CTLA 4 counter receptor B7.2, FUN 1, LAB72
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: Human And More (2) | Immunogen: Recombinant protein Predict reactive species |
| Applications: WB, ELISA | Observed Molecular Weight: 329 aa, 38 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: NM_175862 |
| Conjugate: Unconjugated | Gene Symbol: CD86 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 942 |
| Application: Western Blot (WB) | RRID: ENSG00000114013 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: AB_3670400 |
| Tested Reactivity: Human | Form: Unconjugated |
| Host / Isotype: Mouse / IgG1 | Background Information: CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. |