CD86 Monoclonal antibody proteintech 68674-2-Ig

$449.00
In stock
SKU
68674-2-Ig

 

Activation B7 2 antigen, B7 2, B70, BU63, CD28LG2, CD86, CD86 molecule, CTLA 4 counter receptor B7.2, FUN 1, LAB72

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: Human And More (2) Immunogen: Recombinant protein Predict reactive species
 Applications: WB, ELISA Observed Molecular Weight: 329 aa, 38 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: NM_175862
Conjugate: Unconjugated Gene Symbol: CD86
Tested Applications: Positive WB detected in Gene ID (NCBI): 942
Application: Western Blot (WB) RRID: ENSG00000114013
Dilution: WB : 1:5000-1:50000 Conjugate: AB_3670400
Tested Reactivity: Human Form: Unconjugated
Host / Isotype: Mouse / IgG1 Background Information: CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response.

 

 

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