CD7 Monoclonal antibody proteintech 60209-1-Ig
$449.00
In stock
SKU
60209-1-Ig
1G10D8, CD7 molecule, GP40, LEU-9, T cell antigen CD7
| Host / Isotype: Mouse / IgG1 | Class: Antibody |
| Reactivity: human | Immunogen: CD7 molecule |
| Applications: IHC, IF-P, ELISA | Observed Molecular Weight: BC009293 |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: 924 |
| Conjugate: Unconjugated | Gene Symbol: ENSG00000173762 |
| Tested Applications: Positive IHC detected in | Gene ID (NCBI): AB_10953398 |
| Application: Immunohistochemistry (IHC) | RRID: Unconjugated |
| Dilution: IHC : 1:1600-1:6400 | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Protein G purification |
| Host / Isotype: Monoclonal | Background Information: CD7, also known as Leu-9 or GP40, is a 40-kDa single-pass type I transmembrane glycoprotein belonging to the immunoglobulin superfamily. CD7 is expressed on thymocytes, T cells, NK cells, and cells in the early stages of T, B, and myeloid cell differentiation (PMID: 10530432). It is one of the earliest antigens to appear on cells of the T-lymphocyte lineage (PMID: 3501369). CD7 plays a significant role in T-cell and T-cell/B-cell interactions during early lymphoid development. It is involved in the regulation of cell signaling and biology, including T-cell activation, proliferation, and the expression of interleukin-2 receptor alpha (IL-2Rα) (PMID: 11485208). CD7 is not only a marker for T-cells but also has functional implications in immune cell interactions and adhesion. It can provide co-stimulatory signals and is associated with CD3 and CD45, participating in T-cell activation (PMID: 7523512). |
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