c-Cbl Monoclonal antibody proteintech 66576-1-Ig
$449.00
In stock
SKU
66576-1-Ig
C CBL, CBL, CBL2, c-Cbl, Proto oncogene c Cbl, RING finger protein 55, RNF55
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: Human And More (1) | Immunogen: CatNo: Ag23033 Product name: Recombinant human CBL protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 578-906 aa of BC132733 Sequence: LPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDTSMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMYNIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPKPFPRRINSERKAGSCQQGSGPAASAATASPQLSSEIENLMSQGYSYQDIQKALVIAQNNIEMAKNILREFVSISSPAHVAT Predict reactive species |
| Applications: WB, IHC, ELISA | Observed Molecular Weight: 906 aa, 100 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC132733 |
| Conjugate: Unconjugated | Gene Symbol: CBL |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 867 |
| Application: Western Blot (WB) | RRID: AB_2881936 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: c-Cbl (Casitas B-lineage lymphoma) is a critical regulator that controls immature or follicular helper T cell development, B cell development, immune tolerance, angiogenesis, or tumorigenesis (PMID: 33962939). c-Cbl also plays a pivotal role in regulating dendritic cell (DC) function via negatively modulating IL-12 production after Toll-like receptor (TLR) stimulation (PMID: 21799517). |
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