CBLB Monoclonal antibody proteintech 66353-1-Ig
$449.00
In stock
SKU
66353-1-Ig
CBLB, Nbla00127, RING finger protein 56, RNF56, SH3 binding protein CBL B
| Host / Isotype: Mouse / IgG3 | Class: Monoclonal |
| Reactivity: human, mouse, pig, rat | Immunogen: CatNo: Ag18757 Product name: Recombinant human CBLB protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-352 aa of BC032851 Sequence: MANSMNGRNPGGRGGNPRKGRILGIIDAIQDAVGPPKQAAADRRTVEKTWKLMDKVVRLCQNPKLQLKNSPPYILDILPDTYQHLRLILSKYDDNQKLAQLSENEYFKIYIDSLMKKSKRAIRLFKEGKERMYEEQSQDRRNLTKLSLIFSHMLAEIKAIFPNGQFQGDNFRITKADAAEFWRKFFGDKTIVPWKVFRQCLHEVHQISSGLEAMALKSTIDLTCNDYISVFEFDIFTRLFQPWGSILRNWNFLAVTHPGYMAFLTYDEVKARLQKYSTKPGSYIFRLSCTRLGQWAIGYVTGDGNILQTIPHNKPLFQALIDGSREGFYLYPDGRSYNPDLTGLCEPTPHDH Predict reactive species |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 982 aa, 109 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC032851 |
| Conjugate: Unconjugated | Gene Symbol: CBLB |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 868 |
| Application: Western Blot (WB) | RRID: AB_2881733 |
| Dilution: WB : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: human, mouse, pig, rat | Form: Liquid |
| Host / Isotype: Mouse / IgG3 | Background Information: CBLB(E3 ubiquitin-protein ligase CBL-B) is also known as RNF56 and plays a necessary role to prevent the inappropriate activation of NF-B in response to lipopolysaccharide and to polymicrobial sepsis. CBLB can be phosphorylated on tyrosine and serine residues upon TCR or BCR activation, and upon various types of cell stimulation.. It also has a crucial role in the prevention of chronic inflammation and autoimmunity. This protein has 3 isoforms produced by alternative splicing. |
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