ATG13 Monoclonal antibody proteintech 66708-1-Ig

$449.00
In stock
SKU
66708-1-Ig

 

KIAA0652, 1C3A7, Autophagy related protein 13, Autophagy-related protein 13

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: human, mouse, rat, pig Immunogen: CatNo: Ag12968 Product name: Recombinant human KIAA0652 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 131-481 aa of BC001331 Sequence: ITRVTPAYRLSRKQGHEYVILYRIYFGEVQLSGLGEGFQTVRVGTVGTPVGTITLSCAYRINLAFMSTRQFERTPPIMGIIIDHFVDRPYPSSSPMHPCNYRTAGEDTGVIYPSVEDSQEVCTTSFSTSPPSQLMVPGKEGGVPLAPNQPVHGTQADQERLATCTPSDRTHCAATPSSSEDTETVSNSSEGRASPHDVLETIFVRKVGAFVNKPINQVTLTSLDIPFAMFAPKNLELEDTDPMVNPPDSPETESPLQGSLHSDGSSGGSSGNTHDDFVMIDFKPAFSKDDILPMDLGTFYREFQNPPQLSSLSIDIGAQSMAEDLDSLPEKLAVHEKNVREFDAFVETLQ* Predict reactive species
 Applications: WB, IHC, IF/ICC, FC (Intra), ELISA Observed Molecular Weight: 57 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC001331
Conjugate: Unconjugated Gene Symbol: ATG13
Tested Applications: Positive WB detected in Gene ID (NCBI): 9776
Application: Western Blot (WB) RRID: AB_2882060
Dilution: WB : 1:1000-1:6000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat, Pig Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: ATG13 is one component protein of the ULK1 complex which is required for autophagosome formation and mitophagy. ATG13 has two nutrient regulatory phosphorylation sites and the phosphorylation status of ATG13 affect regulation of autophagy by modulating enzyme activity and cellular localization of ULK1. Besides, it has been reported the nonautophagic function of ATG13 on cardiac development for ATG13-deficient embryos show myocardial growth defects.(PMID:27387056, 26801615, 26644405)

 

 

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