Anti-Human CD25/IL-2RA (BC96) proteintech 65096-1-Ig
$80.00
In stock
SKU
65096-1-Ig
CD25, BC96, IL2 RA, IL 2R subunit alpha, IL 2 receptor subunit alpha
| Host / Isotype: Mouse / IgG1, kappa | Class: Monoclonal |
| Reactivity: human | Immunogen: N/A Predict reactive species |
| Applications: FC | Observed Molecular Weight: 272 aa, 31 kDa |
| Formulation: PBS, Azide | GenBank Accession Number: IL2RA |
| Conjugate: Unconjugated | Gene Symbol: 3559 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): AB_2918398 |
| Application: Flow Cytometry (FC) | RRID: Unconjugated |
| Dilution: FC : 0.2 ug per 10^6 cells in 100 μl suspension | Conjugate: Liquid |
| Tested Reactivity: Human | Form: Affinity purification |
| Host / Isotype: Mouse / IgG1, kappa | Background Information: Proliferation of T lymphocytes is triggered by the interaction of IL-2 with its specific receptor following T lymphocyte activation. The receptor for IL-2 has three forms, generated by different combinations of three different proteins, the alpha chain (IL-2R alpha), the beta chain (IL-2R beta), and the gamma chain (IL-2R gamma) (PMID: 8476561). IL-2R alpha (also known as CD25) is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. CD25 is also found on natural CD4+Foxp3+ Treg cells and a subset of human CD4+ memory T cells (PMID: 22585674). |
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