ANGPTL4 Monoclonal antibody proteintech 67577-1-Ig
$449.00
In stock
SKU
67577-1-Ig
Angiopoietin-related protein 4, Angiopoietin-like protein 4, Angiopoietin related protein 4, Angiopoietin like protein 4, angiopoietin like 4
| Host / Isotype: Mouse / IgG2b | Class: Monoclonal |
| Reactivity: human, mouse | Immunogen: CatNo: Ag30070 Product name: Recombinant human ANGPTL4 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-374 aa of BC023647 Sequence: MSGAPTAGAALMLCAATAVLLSAQGGPVQSKSPRFASWDEMNVLAHGLLQLGQGLREHAERTRSQLSALERRLSACGSACQGTEGSTDLPLAPESRVDPEVLHSLQTQLKAQNSRIQQLFHKVAQQQRHLEKQHLRIQHLQSQFGLLDHKHLDHEVAKPARRKRLPEMAQPVDPAHNVSRLHRLPRDCQELFQVGERQSGLFEIQPQGSPPFLVNCKMTSDGGWTVIQRRHDGSVDFNRPWEAYKAGFGDPHGEFWLGLEKVHSITGDRNSRLAVQLRDWDGNAELLQFSVHLGGEDTAYSLQLTAPVAGQLGATTVPPSGLSVPFSTWDQDHDLRRDKNCAKSLSGGWWFGTCSHSNLNGQYFRSIPQQRQKL Predict reactive species |
| Applications: WB, IF/ICC, ELISA | Observed Molecular Weight: 45 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC023647 |
| Conjugate: Unconjugated | Gene Symbol: ANGPTL4 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 51129 |
| Application: Western Blot (WB) | RRID: AB_2882790 |
| Dilution: WB : 1:1000-1:5000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse | Form: Liquid |
| Host / Isotype: Mouse / IgG2b | Background Information: Angiopoietin-like protein 4 (ANGPTL4), a member of the angiopoietin-like protein subfamily, is a secretory protein that functions as an important modulator of glucose and lipid metabolism. ANGPTL4 inhibits lipoprotein lipase (LPL)-dependent lipolysis thereby limiting the uptake of free fatty acids. Overexpression of ANGPTL4 results in hypertriglyceridemia, while ANGPTL4 deficiency suppresses foam formation in macrophages and protects against atherosclerosis. ANGPTL4 may play a role in several cancers and it also has been shown to prevent the metastatic process by inhibiting vascular activity as well as tumor cell motility and invasiveness. Decreased expression of this protein has been associated with type 2 diabetes. ANGPTL4 has three isoforms, 45 kDa, 41 kDa and 27 kDa. |
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