ALDH2 Monoclonal antibody proteintech 68237-1-Ig

$449.00
In stock
SKU
68237-1-Ig

 

ALDH class 2, ALDH E2, ALDH2, ALDHI, ALDM

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: Human, Mouse, Rat, Rabbit, Pig And More (1) Immunogen: CatNo: Ag7463 Product name: Recombinant human ALDH2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 166-517 aa of BC002967 Sequence: DFFSYTRHEPVGVCGQIIPWNFPLLMQAWKLGPALATGNVVVMKVAEQTPLTALYVANLIKEAGFPPGVVNIVPGFGPTAGAAIASHEDVDKVAFTGSTEIGRVIQVAAGSSNLKRVTLELGGKSPNIIMSDADMDWAVEQAHFALFFNQGQCCCAGSRTFVQEDIYDEFVERSVARAKSRVVGNPFDSKTEQGPQVDETQFKKILGYINTGKQEGAKLLCGGGIAADRGYFIQPTVFGDVQDGMTIAKEEIFGPVMQILKFKTIEEVVGRANNSTYGLAAAVFTKDLDKANYLSQALQAGTVWVNCYDVFGAQSPFGGYKMSGSGRELGEYGLQAYTEVKTVTVKVPQKNS Predict reactive species
 Applications: WB, ELISA Observed Molecular Weight: 56 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC002967
Conjugate: Unconjugated Gene Symbol: ALDH2
Tested Applications: Positive WB detected in Gene ID (NCBI): 217
Application: Western Blot (WB) RRID: AB_2935324
Dilution: WB : 1:5000-1:50000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat, Rabbit, Pig Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: Acetaldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. It mediates NADP+-dependent oxidation of aldehydes into acids during detoxification of alcohol-derived acetaldehyde; lipid peroxidation; and metabolism of corticosteroids, biogenic amines and neurotransmitters. Genetic variation in ALDH2 is responsible for individual differences in responses to drinking alcohol. Thus, the absence of this enzyme is linked to alcohol intolerance and a reduced risk for alcoholism-related liver disease.

 

 

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