UAP1 Monoclonal antibody proteintech 67545-1-Ig
$449.00
In stock
SKU
67545-1-Ig
2C7B2, AgX, AGX 2, AGX1, Antigen X
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human | Immunogen: CatNo: Ag9513 Product name: Recombinant human UAP1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-352 aa of BC009377 Sequence: MNINDLKLTLSKAGQEHLLRFWNELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSYQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSSDGRLLFNAGNIANHFFTVPFLRDVVNVYEPQLQHH Predict reactive species |
| Applications: WB, IHC, IF/ICC, CoIP, ELISA | Observed Molecular Weight: 505 aa, 57 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC009377 |
| Conjugate: Unconjugated | Gene Symbol: UAP1 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 6675 |
| Application: Western Blot (WB) | RRID: AB_2882762 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: UAP1 can convert UTP and GlcNAc-1-P into UDP-GlcNAc, it can also convert UTP and GalNAc-1-P into UDP-GalNAc. There are three isoforms of UAP1, among which isoform ?AGX1 ?has 2 to 3 times higher activity towards GalNAc-1-P, while isoform ?AGX2 ?has 8 times more activity towards GlcNAc-1-P. It has been reported that UAP1 is specific and highly expressed in prostate cancer. UAP1 can protect cells against inhibitors of N-linked glycosylation. UAP1 may play an important role in maintaining INS responsiveness. 67545-1-Ig detects 57 and 59 kDa isoforms in SDS-PAGE.(PMID:25241896) |
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