PLCG2 Monoclonal antibody proteintech 67011-1-Ig
$449.00
In stock
SKU
67011-1-Ig
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, 2F8H5, EC:3.1.4.11, Phosphoinositide phospholipase C-gamma-2, Phospholipase C gamma 2
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human | Immunogen: CatNo: Ag24355 Product name: Recombinant human PLCG2 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 150-313 aa of BC007565 Sequence: IYSVDQTRRNSISLRELKTILPLINFKVSSAKFLKDKFVEIGAHKDELSFEQFHLFYKKLMFEQQKSILDEFKKDSSVFILGNTDRPDASAVYLRDFQRFLIHEQQEHWAQDLNKVRERMTKFIDDTMRETAEPFLFVDEFLTYLFSRENSIWDEKYDAVDMQD Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 148 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC007565 |
| Conjugate: Unconjugated | Gene Symbol: PLCG2 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 5336 |
| Application: Western Blot (WB) | RRID: AB_2882328 |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: Phospholipase C-gamma2 (PLCG2) is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor.IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. |
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