MYL3 Monoclonal antibody proteintech 66286-1-Ig
$449.00
In stock
SKU
66286-1-Ig
Cardiac myosin light chain 1, CMH8, CMLC1, MLC1SB, MLC1V, MYL3, Myosin light chain 3, VLC1
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human, rat, mouse, pig | Immunogen: CatNo: Ag24535 Product name: Recombinant human MYL3 protein Source: e coli.-derived, PET30a Tag: 6*His Domain: 1-195 aa of BC009790 Sequence: MAPKKPEPKKDDAKAAPKAAPAPAPPPEPERPKEVEFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGERLTEDEVEKLMAGQEDSNGCINYEAFVKHIMSS Predict reactive species |
| Applications: WB, IHC, RIP, ELISA | Observed Molecular Weight: 22 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC009790 |
| Conjugate: Unconjugated | Gene Symbol: MYL3 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 4634 |
| Application: Western Blot (WB) | RRID: AB_2881669 |
| Dilution: WB : 1:5000-1:50000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Rat, Mouse, Pig | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: MYL3, also named as MLC1v, is an essential light chain of myosin that is associated with muscle contraction. It is expressed in ventricular and slow skeletal muscle. MYL3 may serve as a target for caspase-3 in dying cardiomyocytes. Mutations of MYL3 gene cause hypertrophic cardiomyopathy. MYL3 has been identified as potential serum biomarker for drug induced myotoxicity. Great increase in MYL3 serum concentration has been observed in rats with cardiac and skeletal muscle injury. (PMID:21685905) |
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