CNOT1 Monoclonal antibody proteintech 66507-1-Ig

$449.00
In stock
SKU
66507-1-Ig

 

1A10A11, AD 005, AD-005, CCR4-associated factor 1, CCR4-NOT transcription complex subunit 1

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: human, mouse, rat, pig Immunogen: CatNo: Ag5623 Product name: Recombinant human CNOT1 protein Source: e coli.-derived, T-HIS Tag: 6*His Domain: 1-354 aa of BC040523 Sequence: MNLDSLSLALSQISYLVDNLTKKNYRASQQEIQHIVNRHGPEADRHLLRCLFSHVDFSGDGKSSGKDFHQTQFLIQECALLITKPNFISTLSYAIDNPLHYQKSLKPAPHLFAQLSKVLKLSKVQEVIFGLALLNSSSSDLRGFAAQFIKQKLPDLLRSYIDADVSGNQEGGFQDIAIEVLHLLLSHLLFGQKGAFGVGQEQIDAFLKTLRRDFPQERCPVVLAPLLYPEKRDILMDRILPDSGGVAKTMMESSLADFMQEVGYGFCASIEECRNIIVQFGVREVTAAQVARVLGMMARTHSGLTDGIPLQSISAPGSGIWSDGKDKSDGAQAHTWNVEVLIDVLKELNPSLNF Predict reactive species
 Applications: WB, IHC, IF/ICC, ELISA Observed Molecular Weight: 267 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC040523
Conjugate: Unconjugated Gene Symbol: CNOT1
Tested Applications: Positive WB detected in Gene ID (NCBI): 23019
Application: Western Blot (WB) RRID: AB_2881870
Dilution: WB : 1:2000-1:10000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse, Rat, Pig Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: CNOT1 is a component of CCR4-NOT protein complex, which is a regulator of RNA polymerase II transcription, acts as a transcription repressor. CCR4-NOT complex could participate in transcription as well as mRNA degradation. It's highly expressed in brain, heart, thymus, but weak in skeletal muscle and colon. CNOT1 undergoes alternative splicing to produce four isoforms. CNOT1 exsits as many isoforms. The isoform one is about 267 kDa and the isoform four is about 173 kDa.

 

 

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