Anti-Mouse CD16/CD32 (2.4G2) proteintech 65080-1-Ig
$200.00
In stock
SKU
65080-1-Ig
CD32, 2.4G2, Fc gamma receptor IIB, Fc-gamma RII, Fc-gamma-RIIB
| Host / Isotype: Rat / IgG2b, kappa | Class: Monoclonal |
| Reactivity: mouse | Immunogen: N/A Predict reactive species |
| Applications: FC | Observed Molecular Weight: BC038070 |
| Formulation: PBS, Azide | GenBank Accession Number: 14130 |
| Conjugate: Unconjugated | Gene Symbol: AB_2918383 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.5 ug per 10^6 cells in 100 μl suspension | Conjugate: Affinity purification |
| Tested Reactivity: Mouse | Form: P08101 |
| Host / Isotype: Rat / IgG2b, kappa | Background Information: CD16 (FcγRIII) is a 50-70 kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD32 (FcγRII) is a 40 kD transmembrane glycoprotein that binds to the Fc region of IgG with low affinity. CD32 is present on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. The 2.4G2 antibody reacts with the extracellular domains of mouse CD16 (FcRIII) and CD32 (FcRII) (PMID: 90108; 8406898). Rat anti mouse CD16/CD32 antibody, clone 2.4G2 is specific to the common epitope of CD16 and CD32. It can be used for blocking non-specific binding of immunoglobulins to the Fc receptors by preincubating the cells with the purified antibody at 1 ug per million cells in 100 uL volume for 5-10 minutes prior to immunostaining. |
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