Anti-Human PD-L1/CD274 (29E.2A3) proteintech 65081-1-Ig
$50.00
In stock
SKU
65081-1-Ig
CD274, PD-L1, PD L1, hPD-L1, B7-H1
| Host / Isotype: Mouse / IgG2b, kappa | Class: Monoclonal |
| Reactivity: human | Immunogen: Full length human PD-L1 Predict reactive species |
| Applications: FC | Observed Molecular Weight: BC069381 |
| Formulation: PBS, Azide | GenBank Accession Number: 29126 |
| Conjugate: Unconjugated | Gene Symbol: AB_2918384 |
| Tested Applications: Positive FC detected in | Gene ID (NCBI): Unconjugated |
| Application: Flow Cytometry (FC) | RRID: Liquid |
| Dilution: FC : 0.2 ug per 10^6 cells in 100 μl suspension | Conjugate: Affinity purification |
| Tested Reactivity: Human | Form: Q9NZQ7 |
| Host / Isotype: Mouse / IgG2b, kappa | Background Information: Programmed cell death ligand 1 (PD-L1, CD274, or B7-H1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. PD-L1 is suggested as a negative regulator of T and B cell, and plays important role in mediating tolerance of lymphocytes to self-antigens. It is also involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PD-1-independent manner. |
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