Anti-Human CD86 (BU63) proteintech 65165-1-Ig
$105.00
In stock
SKU
65165-1-Ig
Activation B7 2 antigen, Activation B7-2 antigen, B7 2, B70, BU63
| Host / Isotype: Mouse / IgG1, kappa | Class: Monoclonal |
| Reactivity: Human And More (1) | Immunogen: B-lymphoblastoid cell line ARH 77 Predict reactive species |
| Applications: IF/ICC, FC | Observed Molecular Weight: 329 aa, 38 kDa |
| Formulation: PBS, Azide | GenBank Accession Number: CD86 |
| Conjugate: Unconjugated | Gene Symbol: 942 |
| Tested Applications: Positive IF/ICC detected in | Gene ID (NCBI): ENSG00000114013 |
| Application: Immunofluorescence (IF)/ICC | RRID: AB_2881481 |
| Dilution: IF/ICC : 1:500-1:2000 | Conjugate: Unconjugated |
| Tested Reactivity: Human | Form: Liquid |
| Host / Isotype: Mouse / IgG1, kappa | Background Information: CD86 (also known as B7.2) is a costimulatory molecule belonging to the immunoglobulin superfamily. Primarily expressed on antigen-presenting cells (APCs), including B cells, dendritic cells, and macrophages, CD86 is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of CD86 with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of CD86 with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. |
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