DNAJB6 Monoclonal antibody proteintech 66587-1-Ig
$449.00
In stock
SKU
66587-1-Ig
DJ4, DnaJ, Heat shock protein J2, HHDJ1, HSJ 2
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: human, mouse, rat, pig | Immunogen: CatNo: Ag2258 Product name: Recombinant human DNAJB6 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-241 aa of BC000177 Sequence: MVDYYEVLGVQRHASPEDIKKAYRKLALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFEDFFGNRRGPRGSRSRGTGSFFSAFSGFPSFGSGFSSFDTGFTSFGSLGHGGLTSFSSTSFGGSGMGNFKSISTSTKMVNGRKITTKRIVENGQERVEVEEDGQLKSLTINGKEQLLRLDNK Predict reactive species |
| Applications: WB, IHC, IF/ICC, ELISA | Observed Molecular Weight: 241 aa, 27 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC000177 |
| Conjugate: Unconjugated | Gene Symbol: DNAJB6 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 10049 |
| Application: Western Blot (WB) | RRID: AB_2881947 |
| Dilution: WB : 1:2000-1:8000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Mouse, Rat, Pig | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: DNAJB6, belongs to the heat shock protein 40 (HSP40) family, a noncanonical member of the DNAJ-chaperone family, is mainly expressed in neurons. It plays an important role in recovery from misfolded protein aggregates (PMID: 27276715). As seen by the western blot stained for DNAJB6, there are 2 splice forms of the protein resulting in a longer isoform (38?kDa) and a shorter one (27?kDa). DNAJB6 (27?kDa) isoform but not DNAJB6 (38?kDa) isoform is effective with suppressing cytoplasmic protein aggregation (PMID: 20159555). The antibody 66587-1-Ig recognizes both isoforms. |
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