CISD2-Specific Monoclonal antibody proteintech 66082-1-Ig
$449.00
In stock
SKU
66082-1-Ig
CDGSH iron sulfur domain 2, CDGSH2, CISD2, CISD2-Specific, ERIS, Miner1, MitoNEET related 1 protein, NAF 1, WFS2, ZCD2
| Host / Isotype: Mouse / IgG2b | Class: Monoclonal |
| Reactivity: human, zebrafish, rat, mouse | Immunogen: Fusion Protein Predict reactive species |
| Applications: WB, IHC, IF/ICC, CoIP, ELISA | Observed Molecular Weight: 15 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: CISD2 |
| Conjugate: Unconjugated | Gene Symbol: 493856 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): AB_11232425 |
| Application: Western Blot (WB) | RRID: Unconjugated |
| Dilution: WB : 1:2000-1:16000 | Conjugate: Liquid |
| Tested Reactivity: human, zebrafish, rat, mouse | Form: Protein A purification |
| Host / Isotype: Mouse / IgG2b | Background Information: CISD2 gene encodes a 15 kDa CDGSH iron-sulfur domain-containing protein 2, which is also named Miner1 or NAF-1, this protein was reported on endoplasmic reticulum membrane or mitochondrion outer membrane. Defects in CISD2 are the cause of Wolfram syndrome type 2 (WFS2), a rare disorder characterized by juvenile-onset insulin-dependent diabetes mellitus with optic atrophy. CISD2 regulates autophagy program by interacting BCL2, contributing to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. This monoclonal antibody is specific to CISD2 and does not cross-react with CISD1. |
Reviews
Write Your Own Review
Related Products
Check items to add to the cart or
