PRX5 Monoclonal antibody proteintech 67599-1-Ig
$449.00
In stock
SKU
67599-1-Ig
Peroxiredoxin 5, PRDX5, 1B8C5, ACR 1, ACR1
| Host / Isotype: Mouse / IgG1 | Class: Monoclonal |
| Reactivity: Human, Rat And More (1) | Immunogen: CatNo: Ag12262 Product name: Recombinant human Prx5 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-214 aa of BC110983 Sequence: MGLAGVCALRRSAGYILVGGAGGQSAAAAARRCSEGEWASGGVRSFSRAAAAMAPIKVGDAIPAVEVFEGEPGNKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGFVEQAEALKAKGVQVVACLSVNDAFVTGEWGRAHKAEGKVRLLADPTGAFGKETDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKALNVEPDGTGLTCSLAPNIISQL Predict reactive species |
| Applications: WB, IHC, IF/ICC, IP, ELISA | Observed Molecular Weight: 214 aa, 22 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC110983 |
| Conjugate: Unconjugated | Gene Symbol: PRX5 |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 25824 |
| Application: Western Blot (WB) | RRID: AB_2882805 |
| Dilution: WB : 1:2000-1:10400 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Rat | Form: Liquid |
| Host / Isotype: Mouse / IgG1 | Background Information: Peroxiredoxin 5 (Prx5) is a member of a family consisting of six antioxidant enzymes. Prx5 is ubiquitously expressed in various tissues including mitochondria and peroxisomes, implying that Prx5 functions as a regulator of the cellular oxidation state. Prx5 plays a critical role in protecting cells from oxidative stress by inhibiting the accumulation of reactive oxygen species and cell death. Prx5 has an intensive ROS scavenging activity because it is located in the cytosol and mitochondria. Prx5 expression was upregulated during adipogenesis and Prx5 overexpression suppressed adipogenesis by regulating cytosolic and mitochondrial ROS generation. (PMID: 29777756, PMID: 31505325, PMID: 22020876) |
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