MMS19 Monoclonal antibody proteintech 66049-1-Ig

$449.00
In stock
SKU
66049-1-Ig

 

hMMS19, MET18, MET18 homolog, MMS19, MMS19 like protein, MMS19L

Host / Isotype: Mouse / IgG2b Class: Monoclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag8960 Product name: Recombinant human MMS19 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 457-803 aa of BC006575 Sequence: FLDGNVSFLPENSFPSRFQPFQDGSSGQRRLIALLMAFVCSLPRNVEIPQLNQLMRELLELSCCHSCPFSSTAAAKCFAGLLNKHPAGQQLDEFLQLAVDKVEAGLDSGPCRSQAFTLLLWVTKALVLRYHPLSSCLTARLMGLLSDPELGPAAADGFSLLMSDCTDVLTRAGHAEVRIMFRQRFFTDNVPALVQGFHAAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCPDCVVQLSTLSCLQPLLLEAPQVMSLHVDTLVTKFLNLSSSPSMAVRIAALQCMHALTRLPTPVLLPYKPQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, ELISA Observed Molecular Weight: 1030 aa, 113 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC006575
Conjugate: Unconjugated Gene Symbol: MMS19
Tested Applications: Positive WB detected in Gene ID (NCBI): 64210
Application: Western Blot (WB) RRID: AB_11041708
Dilution: WB : 1:1000-1:4000 Conjugate: Unconjugated
Tested Reactivity: human, mouse, rat Form: Liquid
Host / Isotype: Mouse / IgG2b Background Information: MMS19 (MMS19 nucleotide excision repair homolog), also known as MET18, is a 1,030 amino acid nuclear protein containing seven HEAT repeats that belongs to the MET18/MMS19 family. Via its interactions with TFIIH p80 and TFIIH p89 helicases, MMS19 plays a role in nucleotide excision repair (NER) and RNA polymerase II (Pol II) transcription. MMS19 may also function as a transcriptional coactivator of estrogen receptor. While ubiquitously expressed, highest levels of MMS19 have been found in testis. At least five distinct MMS19 protein isoforms exist, which are produced by alternative splicing events.

 

 

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