SEC5/EXOC2 Monoclonal antibody proteintech 66011-1-Ig

$449.00
In stock
SKU
66011-1-Ig

 

EXOC2, exocyst complex component 2, Exocyst complex component Sec5, SEC5, SEC5/EXOC2, SEC5L1, Sec5p

Host / Isotype: Mouse / IgG2b Class: Monoclonal
Reactivity: human, mouse, pig, rat Immunogen: CatNo: Ag17866 Product name: Recombinant human SEC5 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 456-806 aa of BC016918 Sequence: TIQDLILDLRVRCVMATLQHTAEEIKRLAEKEDWIVDNEGLTSLPCQFEQCIVCSLQSLKGVLECKPGEASVFQQPKTQEEVCQLSINIMQVFIYCLEQLSTKPDADIDTTHLSVDVSSPDLFGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKELDQRLFENYIELKADPIVGSLEPGIYAGYFDWKDCLPPTGVRNYLKEALVNIIAVHAEVFTISKELVPRVLSKVIEAVSEELSRLMQCVSSFSKNGALQARLEICALRDTVAVYLTPESKSSFKQALEALPQLSSGADKKLLEELLNKFKSSMHLQLTCFQAASSTMMKT Predict reactive species
 Applications: WB, IHC, IF/ICC, IP, ELISA Observed Molecular Weight: 924 aa, 104 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC016918
Conjugate: Unconjugated Gene Symbol: SEC5
Tested Applications: Positive WB detected in Gene ID (NCBI): 55770
Application: Western Blot (WB) RRID: AB_11042317
Dilution: WB : 1:2500-1:10000 Conjugate: Unconjugated
Tested Reactivity: human, mouse, pig, rat Form: Liquid
Host / Isotype: Mouse / IgG2b Background Information: EXOC2 (exocyst complex component 2), also known as SEC5 and SEC5L1, is a component of the exocyst complex, and is required to mediate RalB-dependent survival signals in transformed cells. The exocyst complex, composed of eight evolutionarily conserved subunits (SEC3, SEC5, SEC6, SEC8, SEC10, SEC15, EXO70, and EXO84), is involved in tethering post-Golgi secretory vesicles to specific plasma membrane domains. The gene of EXOC2 maps to chromosome 6p25.3, and encodes a 924-amino acid protein with an experimentally determined molecular mass of 95-100 kDa. EXOC2 mRNA is widely expressed with highest levels in brain and placenta.

 

 

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