human IgM Monoclonal antibody proteintech 66484-1-Ig

$449.00
In stock
SKU
66484-1-Ig

 

IGHM, IgM, 2D10B10, MU, VH

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: human Immunogen: CatNo: Ag1459 Product name: Recombinant human IGHM protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-351 aa of BC009851 Sequence: FGNPRKSKLICQATGFSPRQIQVSWLREGKQVGSGVTTDQVQAEAKESGPTTYKVTSTLTIKESDWLSQSMFTCRVDHRGLTFQQNASSMCVPDQDTAIRVFAIPPSFASIFLTKSTKLTCLVTDLTTYDSVTISWTRQNGEAVKTHTNISESHPNATFSAVGEASICEDDWNSGERFTCTVTHTDLPSPLKQTISRPKGVALHRPDVYLLPPAREQLNLRESATITCLVTGFSPADVFVQWMQRGQPLSPEKYVTSAPMPEPQAPGRYFAHSILTVSEEEWNTGETYTCVVAHEALPNRVTERTVDKSTEGEVSADEEGFENLWATASTFIVLFLLSLFYSTTVTLFKVK Predict reactive species
 Applications: WB, IHC, IF-P, IP, ELISA Observed Molecular Weight: 69 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC009851
Conjugate: Unconjugated Gene Symbol: IGHM
Tested Applications: Positive WB detected in Gene ID (NCBI): 3507
Application: Western Blot (WB) RRID: AB_2881850
Dilution: WB : 1:5000-1:20000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Mouse / IgG1 Background Information: IGHM is the constant region of heavy chain of IgM. IgM is the first immunoglobulin expressed during B cell development. IgM antibodies play an important role in primary immune response involved in early recognition of external invaders like bacteria and viruses, cellular waste and modified self, as well as in recognition and elimination of precancerous and cancerous lesions. The μ heavy chain disease is a rare lymphoproliferative disorder. Human immunoglobulin heavy chain locus translocations are associated with leukaemias and lymphomas, including multiple myeloma, mantle cell lymphoma, Burkitt's lymphoma and diffuse large B cell lymphoma. This antibody detects the heavy chain of human IgM (~75 kDa).

 

 

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