ULK1 Monoclonal antibody proteintech 68445-1-Ig

$449.00
In stock
SKU
68445-1-Ig

 

1D7G1, ATG1, Autophagy-related protein 1 homolog, EC:2.7.11.1, hATG1

Host / Isotype: Mouse / IgG1 Class: Monoclonal
Reactivity: human, mouse, rat Immunogen: CatNo: Ag22397 Product name: Recombinant human ULK1 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 17-466 aa of NM_003565 Sequence: SRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLLGKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQQIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAATLCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQASSPQDLRLFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPVPVPSYPSSGSGSSSSSSSTSHLASPPSLGEMQQLQKTLASPADTAGFLHSSRDSGGSKDSSCDTDDFVMVPAQFPGDLVAEAPSAKPPPDSLMCSGSSLVASAGLESHGRTPSPSPPCSSSPSPSGRAGPFSSSRCGASVPIPVPTQVQNYQRIERNLQSPTQFQTPRSSAIRRSG Predict reactive species
 Applications: WB, IHC, ELISA Observed Molecular Weight: 130-150 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: ULK1
Conjugate: Unconjugated Gene Symbol: 8408
Tested Applications: Positive WB detected in Gene ID (NCBI): AB_3085157
Application: Western Blot (WB) RRID: Unconjugated
Dilution: WB : 1:5000-1:50000 Conjugate: Liquid
Tested Reactivity: Human, Mouse, Rat Form: Protein G purification
Host / Isotype: Mouse / IgG1 Background Information: ULK1, also named as KIAA0722, belongs to the protein kinase superfamily, Ser/Thr protein kinase family and APG1/unc-51/ULK1 subfamily. It is involved in autophagy. ULK1 is required for autophagosome formation. It forms a stable complex with Atg13 and focal adhesion kinase (FAK) family interacting protein of 200?kDa?(FIP 200)(PMID:21460634). ULK1 phosphorylates ATG13/KIAA0652. It is involved in axon growth. ULK1 plays an essential role in neurite extension of cerebellar granule cells. ULK1 represents a potential novel prognostic biomarker for HCC patients and may play an important role during the progression of HCC(PMID:23573318).

 

 

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