HDAC4 Monoclonal antibody proteintech 66838-1-Ig

$449.00
In stock
SKU
66838-1-Ig

 

KIAA0288, HD4, EC:3.5.1.98, 1D2G12

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: human, mouse Immunogen: CatNo: Ag11345 Product name: Recombinant human HDAC4 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 623-972 aa of BC039904 Sequence: SKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEEEPPL Predict reactive species
 Applications: WB, IHC, IF/ICC, IF-P, IP, ChIP, ELISA Observed Molecular Weight: 972 aa, 106 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC039904
Conjugate: Unconjugated Gene Symbol: HDAC4
Tested Applications: Positive WB detected in Gene ID (NCBI): 9759
Application: Western Blot (WB) RRID: AB_2882181
Dilution: WB : 1:1000-1:3000 Conjugate: Unconjugated
Tested Reactivity: Human, Mouse Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: HDAC4, also named as HDACA, belongs to the histone deacetylase family. HDAC4 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. HDAC4 is Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.

 

 

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