CD74 Monoclonal antibody proteintech 66390-1-Ig

$449.00
In stock
SKU
66390-1-Ig

 

Ia antigen-associated invariant chain, HLA-DR antigens-associated invariant chain, HLADG, DHLAG, Class-II-associated invariant chain peptide

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: human Immunogen: CatNo: Ag25503 Product name: Recombinant human CD74 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-48 aa of BC018726 Sequence: MHRRRSRSCREDQKPVMDDQRDLISNNEQLPMLGRRPGAPESKCSRGA Predict reactive species
 Applications: WB, IF/ICC, ELISA Observed Molecular Weight: 34 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC018726
Conjugate: Unconjugated Gene Symbol: CD74
Tested Applications: Positive WB detected in Gene ID (NCBI): 972
Application: Western Blot (WB) RRID: AB_2881766
Dilution: WB : 1:1000-1:6000 Conjugate: Unconjugated
Tested Reactivity: Human Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: CD74, also known as MHC class II invariant chain Ii or HLA-DR-associated invariant chain, is a non-polymorphic type II transmembrane glycoprotein. CD74 is mainly distributed in B cells, monocytes, Langerhans cells, dendritic cells and thymic epithelial cells, and is also expressed in epithelial cells. CD74 plays a key role in MHC class II antigen processing and also serves as a cell surface receptor for the macrophage cytokine MIF. CD74 plays an important role in cardiovascular diseases such as atherosclerosis, ischemic heart disease, and myocardial hypertrophy.(PMID: 15475450; PMID: 27752708; PMID: 38992165;PMID: 36712241).

 

 

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