5 Lipoxygenase Monoclonal antibody proteintech 66326-1-Ig

$449.00
In stock
SKU
66326-1-Ig

 

ALOX5, 3B1B7, 5 LO, 5 LOX, 5-lipoxygenase

Host / Isotype: Mouse / IgG2a Class: Monoclonal
Reactivity: human, pig Immunogen: CatNo: Ag18168 Product name: Recombinant human ALOX5 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-349 aa of BC130332 Sequence: MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWL Predict reactive species
 Applications: WB, IHC, IF, ELISA Observed Molecular Weight: 674 aa, 78 kDa
Formulation: PBS, Azide, Glycerol GenBank Accession Number: BC130332
Conjugate: Unconjugated Gene Symbol: 5 Lipoxygenase
Tested Applications: Positive WB detected in Gene ID (NCBI): 240
Application: Western Blot (WB) RRID: AB_2881707
Dilution: WB : 1:1000-1:4000 Conjugate: Unconjugated
Tested Reactivity: Human, Pig Form: Liquid
Host / Isotype: Mouse / IgG2a Background Information: ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene (cys-LT) production, critical mediators in asthma(PMID:12911785).

 

 

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