5 Lipoxygenase Monoclonal antibody proteintech 66326-1-Ig
$449.00
In stock
SKU
66326-1-Ig
ALOX5, 3B1B7, 5 LO, 5 LOX, 5-lipoxygenase
| Host / Isotype: Mouse / IgG2a | Class: Monoclonal |
| Reactivity: human, pig | Immunogen: CatNo: Ag18168 Product name: Recombinant human ALOX5 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-349 aa of BC130332 Sequence: MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWL Predict reactive species |
| Applications: WB, IHC, IF, ELISA | Observed Molecular Weight: 674 aa, 78 kDa |
| Formulation: PBS, Azide, Glycerol | GenBank Accession Number: BC130332 |
| Conjugate: Unconjugated | Gene Symbol: 5 Lipoxygenase |
| Tested Applications: Positive WB detected in | Gene ID (NCBI): 240 |
| Application: Western Blot (WB) | RRID: AB_2881707 |
| Dilution: WB : 1:1000-1:4000 | Conjugate: Unconjugated |
| Tested Reactivity: Human, Pig | Form: Liquid |
| Host / Isotype: Mouse / IgG2a | Background Information: ALOX5(arachidonate 5-lipoxygenase) is also named as LOG5, 5-LO and belongs to the lipoxygenase family. It catalyzes the first step in leukotriene biosynthesis, and plays a role in inflammatory processes. It is a 78 kDa iron-containing enzyme that translocates from the cytosol to associate with FLAP, and converts arachidonate in two steps into the unstable intermediate LTA4. It is essential for cysteinyl-leukotriene (cys-LT) production, critical mediators in asthma(PMID:12911785). |